Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma

Abstract Hepatoblastoma is the most common malignant pediatric liver cancer. Histological evaluation of tumor biopsies is used to distinguish among the different subtypes of hepatoblastoma, with fetal and embryonal representing the two main epithelial components. With frequent CTNNB1 mutations, hepa...

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Main Authors: Stefania Crippa, Pierre‐Benoit Ancey, Jessica Vazquez, Paolo Angelino, Anne‐Laure Rougemont, Catherine Guettier, Vincent Zoete, Mauro Delorenzi, Olivier Michielin, Etienne Meylan
Format: Article
Language:English
Published: Springer Nature 2017-09-01
Series:EMBO Molecular Medicine
Subjects:
glucose transporter
glycolysis
mutant β‐catenin
pediatric liver cancer
Online Access:https://doi.org/10.15252/emmm.201707814
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https://doi.org/10.15252/emmm.201707814

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