MetArea: a software package for analysis of the mutually exclusive occurrence in pairs of motifs of transcription factor binding sites based on ChIP-seq data

MetArea: a software package for analysis of the mutually exclusive occurrence in pairs of motifs of transcription factor binding sites based on ChIP-seq data

ChIP-seq technology, which is based on chromatin immunoprecipitation (ChIP), allows mapping a set of genomic loci (peaks) containing binding sites (BS) for the investigated (target) transcription factor (TF). A TF may recognize several structurally different BS motifs. The multiprotein complex mappe...

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Bibliographic Details
Main Authors: V. G. Levitsky, A. V. Tsukanov, T. I. Merkulova
Format: Article
Language:English
Published: Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders 2025-01-01
Series:Вавиловский журнал генетики и селекции
Subjects:
<i>de novo</i> motif search
pr curve
area under curve
structural variants of transcription factor binding site motifs
cooperative action of transcription factors
Online Access:https://vavilov.elpub.ru/jour/article/view/4404
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