COEXIST: Coordinated single-cell integration of serial multiplexed tissue images.

Multiplexed tissue imaging (MTI) and other spatial profiling technologies commonly utilize serial tissue sectioning to comprehensively profile samples by imaging each section with unique biomarker panels or assays. The dependence on serial sections is attributed to technological limitations of MTI p...

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Bibliographic Details
Main Authors: Robert T Heussner, Cameron F Watson, Christopher Z Eddy, Kunlun Wang, Eric M Cramer, Allison L Creason, Gordon B Mills, Young Hwan Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013325
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