Ion-exchange chromatography, capillary isoelectric focusing, and capillary zone electrophoresis coupled to mass spectrometry for charge variant analysis of monoclonal antibodies
Monoclonal antibody (mAb) charge variant analysis, which ensures the quality of biopharmaceuticals, is primarily performed by either cation exchange chromatography (CEX), capillary isoelectric focusing (CIEF), or capillary zone electrophoresis (CZE). Though selectivity is different for all methods,...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
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| Series: | mAbs |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/19420862.2025.2537116 |
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