Association of matrix metalloproteinase 7 and the alpha-chain of fibrinogen at baseline with response to methotrexate at 3 months in patients with early rheumatoid arthritis

Association of matrix metalloproteinase 7 and the alpha-chain of fibrinogen at baseline with response to methotrexate at 3 months in patients with early rheumatoid arthritis

Abstract Background The identification of responders to methotrexate (MTX) would optimize the therapy of patients with early rheumatoid arthritis (eRA). Our aim was to identify protein biomarkers for the prediction of the response to MTX. Methods We analysed patients with eRA (N = 135) from the Swed...

Full description

Saved in:
Bibliographic Details
Main Authors: Karen Hambardzumyan, Carl Hamsten, Lucía Lourido, Saedis Saevarsdottir, Peter Nilsson, Ronald F. van Vollenhoven, Per-Johan Jakobsson, Helena Idborg
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Rheumatology
Subjects:
Rheumatoid arthritis
Biomarkers
Prediction
Affinity proteomics
Methotrexate therapy
Clinical response
Online Access:https://doi.org/10.1186/s41927-025-00509-8
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s41927-025-00509-8

Similar Items