Exploring the potential of Gonolobus condurango as a histone deacetylase inhibitor in triple-negative breast cancer cell lines: in vitro study

Abstract Background Triple-negative breast cancer (TNBC) is a subtype associated with poor prognosis, low survival rates, and high expression of histone deacetylases (HDAC). Treatment with HDAC inhibitors (HDACi) induces the acetylation of histones and thereby the expression of tumor suppressive miR...

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Bibliographic Details
Main Authors: Beate Vajen, Vera Schäffer, Marlies Eilers, Brigitte Schlegelberger, Britta Skawran
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Complementary Medicine and Therapies
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Online Access:https://doi.org/10.1186/s12906-025-04896-w
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