Targeting PD-1 post-translational modifications for improving cancer immunotherapy

Programmed cell death protein 1 (PD-1) is a critical immune checkpoint receptor that suppresses immune responses largely through its interaction with PD-L1. Tumors exploit this mechanism to evade immune surveillance, positioning immune checkpoint inhibitors targeting the PD-1/PD-L1 axis as groundbre...

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Bibliographic Details
Main Authors: Jie Shi, Chuan He, Li Chen, Xixin Xing, Wenyi Wei, Jinfang Zhang
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Cell Insight
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772892725000227
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