HIV-associated penile anaerobes disrupt epithelial barrier integrity.

HIV-associated penile anaerobes disrupt epithelial barrier integrity.

Specific anaerobic taxa within the penile microbiome-the Bacteria Associated with Seroconversion, Inflammation and Immune Cells (BASIC) species-enhance HIV-1 susceptibility, in part by recruiting susceptible cells to the inner foreskin. However, their effect on epithelial barrier integrity has not b...

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Main Authors: Lane B Buchanan, Zhongtian Shao, Ronald M Galiwango, Shirley Constable, David Zuanazzi, Victoria Menya Biribawa, Henry Rogers Ssemunywa, Annemarie Namuniina, Brenda Okech, Gabriella Edfeldt, Annelie Tjernlund, Aaron A R Tobian, Daniel E Park, Tony Pham, Maliha Aziz, Juan E Salazar, Sydney Nelson, Cindy M Liu, Rupert Kaul, Jessica L Prodger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1013094
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https://doi.org/10.1371/journal.ppat.1013094

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