Metabolic engineering of Saccharomyces cerevisiae for co-production of ethanol and 3-methyl-1-butanol from sugarcane molasses

Metabolic engineering of Saccharomyces cerevisiae for co-production of ethanol and 3-methyl-1-butanol from sugarcane molasses

Abstract 3-Methyl-1-butanol (3MB) is a promising renewable solvent, drop-in fuel, and precursor for various industrial products, including flavors, fragrances, and surfactants. Due to the myriad of intertwined biosynthetic pathways that share metabolic precursors, conventional metabolic engineering...

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Main Authors: Sasha Yogiswara, Jonas Rombout, Giovanni Micharikopoulos, Sam De Craemer, Beatriz Herrera-Malaver, Lotte van Landschoot, Sofie Mannaerts, Marcelo do Amaral, Karin Voordeckers, Stijn Spaepen, Jan Steensels, Quinten Deparis, Bart Ghesquière, Kevin J. Verstrepen
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
3-Methyl-1-butanol
Isoamyl alcohol
Fusel alcohols
Branched-chain amino acid
Yeast metabolic engineering
Bioethanol production
Online Access:https://doi.org/10.1186/s13068-025-02685-8
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https://doi.org/10.1186/s13068-025-02685-8

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