Bile acid metabolism in multiple sclerosis is perturbed and associated with the risk of confirmed disability worsening

Bile acid metabolism in multiple sclerosis is perturbed and associated with the risk of confirmed disability worsening

Abstract Background Bile acids (BAs) have emerged as important mediators in neuroinflammation and neurodegeneration, important features of multiple sclerosis (MS). This study aimed to examine serum BA levels in newly diagnosed people with MS (pwMS) and explore their association with disability worse...

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Main Authors: Ida Erngren, Aina Vaivade, Henrik Carlsson, Asma Al-Grety, Torbjörn Åkerfeldt, Ingrid Kockum, Anna Karin Hedström, Lars Alfredsson, Tomas Olsson, Joachim Burman, Kim Kultima
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Medicine
Subjects:
Multiple sclerosis
Bile acids
Autoimmune disorder
Confirmed disability worsening
Online Access:https://doi.org/10.1186/s12916-025-04041-x
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https://doi.org/10.1186/s12916-025-04041-x

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