Flo5-1 and Nrg1 are involved in reversible pH-dependent flocculation in Komagataella phaffii

Abstract The non-conventional yeast Komagataella phaffii (syn Pichia pastoris) is a well-established host for biotechnological production processes, especially for recombinant protein production. Such processes are mostly run at neutral or slightly acid pH values between pH 5.0 and 6.5, but K. phaff...

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Bibliographic Details
Main Authors: Sonakshi De, Gerhard Stadlmayr, Corinna Rebnegger, Diethard Mattanovich, Brigitte Gasser
Format: Article
Language:English
Published: Springer 2025-08-01
Series:Applied Microbiology and Biotechnology
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Online Access:https://doi.org/10.1007/s00253-025-13562-7
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