Increased glymphatic system activity and thalamic vulnerability in drug-naive somatic depression: Evidenced by DTI-ALPS index

Increased glymphatic system activity and thalamic vulnerability in drug-naive somatic depression: Evidenced by DTI-ALPS index

Major depressive disorder (MDD) is a significant contributor to global disease burden, with somatic symptoms frequently complicating its diagnosis and treatment. Recent advances in neuroimaging have provided insights into the neurobiological underpinnings of MDD, yet the role of the glymphatic syste...

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Bibliographic Details
Main Authors: Zipeng Deng, Wei Wang, Zhaowen Nie, Simeng Ma, Enqi Zhou, Xinhui Xie, Qian Gong, Lihua Yao, Lihong Bu, Lijun Kang, Zhongchun Liu
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:NeuroImage: Clinical
Subjects:
Somatic depression
Major depressive disorder
Glymphatic system
DTI-ALPS
Thalamus vulnerability
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158225000397
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