Heterozygous interferon signaling deficient mice as animal models for Chikungunya virus infection in the heart

Abstract Although chikungunya virus (CHIKV)-caused cardiovascular diseases are frequently reported in clinics, the underlying mechanisms are poorly understood, which is primarily due to a lack of animal models. In this study, we report that CHIKV infection in homozygous interferon α/β receptor-defic...

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Bibliographic Details
Main Authors: Shazeed-Ul Karim, Farzana Nazneen, Prince M. D. Denyoh, David S. Bai, Damian G. Romero, Fengwei Bai
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-02191-9
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