Hydrogen sulfide as a new therapeutic target of pulmonary hypertension: an overview with update on immunomodulation

Hydrogen sulfide as a new therapeutic target of pulmonary hypertension: an overview with update on immunomodulation

Pulmonary hypertension (PH) is a complex and progressive vascular disease characterized by elevated pulmonary arterial pressure (PAP) and vascular resistance, leading to right ventricular failure and, ultimately, death. Current therapies primarily focus on vasodilation and symptom management, but th...

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Main Authors: Xue-Xue Zhu, Chen-Yang Zhao, Qing-Bo Lu, Ao-Yuan Zhang, Xin-Yu Meng, Jia-Bao Su, Guo Chen, An-Jing Xu, Hai-Jian Sun, Xiao-Wei Nie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
hydrogen sulfide
pulmonary hypertension
oxidative stress
immunomodulation
organosulfur compounds
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1510275/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1510275/full

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