Screening of a Fraction with Higher Amyloid β Aggregation Inhibitory Activity from a Library Containing 210 Mushroom Extracts Using a Microliter-Scale High-Throughput Screening System with Quantum Dot Imaging

Screening of a Fraction with Higher Amyloid β Aggregation Inhibitory Activity from a Library Containing 210 Mushroom Extracts Using a Microliter-Scale High-Throughput Screening System with Quantum Dot Imaging

Alzheimer’s disease (AD) is a highly prevalent neurodegenerative disease hallmarked by amyloid plaques and neurofibrillary tangles. Amyloid plaques are formed by the amyloid β (Aβ) aggregation, so substances that inhibit this aggregation are useful for preventing and treating AD. Mushrooms are widel...

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Main Authors: Gegentuya Huanood, Mahadeva M. M. Swamy, Rina Sasaki, Keiya Shimamori, Masahiro Kuragano, Enkhmaa Enkhbat, Yoshiko Suga, Masaki Anetai, Kenji Monde, Kiyotaka Tokuraku
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Foods
Subjects:
mushroom
quantum dot nanoprobes
amyloid β
Alzheimer’s disease
inhibitor
natural compounds
Online Access:https://www.mdpi.com/2304-8158/13/23/3740
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