Peripheral inflammatory factors as prognostic predictors for first-line PD-1/PD-L1 inhibitors in advanced non-small cell lung cancer

Peripheral inflammatory factors as prognostic predictors for first-line PD-1/PD-L1 inhibitors in advanced non-small cell lung cancer

Abstract Immune checkpoint inhibitors (ICIs) have significantly improved the efficacy and prognosis of patients with non-small cell lung cancer (NSCLC). However, there remains a lack of optimal predictive biomarkers for assessing the response of ICIs. This study aimed to evaluate peripheral inflamma...

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Bibliographic Details
Main Authors: Chen-xing Jin, Yan-song Liu, He-nan Qin, Yi-bin Teng, Rui Sun, Zhong-jing Ma, A-man Wang, Ji-wei Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Non-small cell lung cancer
Immune checkpoint inhibitors
Biomarkers
Immunotherapy respond
Neutrophil to lymphocyte ratio
Systemic inflammatory index
Online Access:https://doi.org/10.1038/s41598-024-84469-y
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https://doi.org/10.1038/s41598-024-84469-y

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