Acute Fatty Liver Disease of Pregnancy in the Second Trimester

Acute fatty liver of pregnancy (AFLP) is a rare disorder that typically presents in the third trimester. We report a case of a 21-year-old woman with a history of intrauterine fetal demise at 19 weeks’ gestation who developed fulminant liver failure 1 week after the fetal demise. She was diagnosed w...

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Main Authors: Faraz Afridi, Michael Feely, Raju Reddy
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2020/6705784
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author Faraz Afridi
Michael Feely
Raju Reddy
author_facet Faraz Afridi
Michael Feely
Raju Reddy
author_sort Faraz Afridi
collection DOAJ
description Acute fatty liver of pregnancy (AFLP) is a rare disorder that typically presents in the third trimester. We report a case of a 21-year-old woman with a history of intrauterine fetal demise at 19 weeks’ gestation who developed fulminant liver failure 1 week after the fetal demise. She was diagnosed with AFLP as per the Swansea criteria. An orthotopic liver transplant was attempted but was unsuccessful. AFLP usually presents between the 30th to 38th weeks of gestation. However, it can occur in the postpartum period after only 19 weeks of gestation as highlighted in our case.
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series Case Reports in Critical Care
spelling doaj-art-2e0daeb837ba4c62bbef48b88ef6a8b32025-02-03T01:01:56ZengWileyCase Reports in Critical Care2090-64202090-64392020-01-01202010.1155/2020/67057846705784Acute Fatty Liver Disease of Pregnancy in the Second TrimesterFaraz Afridi0Michael Feely1Raju Reddy2Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, P.O. Box 100225, Gainesville, FL 32610-0225, USADivision of Pathology, Immunology and Laboratory Medicine. Department of Medicine, University of Florida, 1600 SW Archer Road, PO Box 100275, Gainesville, FL 32610-0275, USADivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, College of Medicine, University of Florida, 1600 SW Archer Road, P.O. Box 100225, Gainesville, FL 32610-0225, USAAcute fatty liver of pregnancy (AFLP) is a rare disorder that typically presents in the third trimester. We report a case of a 21-year-old woman with a history of intrauterine fetal demise at 19 weeks’ gestation who developed fulminant liver failure 1 week after the fetal demise. She was diagnosed with AFLP as per the Swansea criteria. An orthotopic liver transplant was attempted but was unsuccessful. AFLP usually presents between the 30th to 38th weeks of gestation. However, it can occur in the postpartum period after only 19 weeks of gestation as highlighted in our case.http://dx.doi.org/10.1155/2020/6705784
spellingShingle Faraz Afridi
Michael Feely
Raju Reddy
Acute Fatty Liver Disease of Pregnancy in the Second Trimester
Case Reports in Critical Care
title Acute Fatty Liver Disease of Pregnancy in the Second Trimester
title_full Acute Fatty Liver Disease of Pregnancy in the Second Trimester
title_fullStr Acute Fatty Liver Disease of Pregnancy in the Second Trimester
title_full_unstemmed Acute Fatty Liver Disease of Pregnancy in the Second Trimester
title_short Acute Fatty Liver Disease of Pregnancy in the Second Trimester
title_sort acute fatty liver disease of pregnancy in the second trimester
url http://dx.doi.org/10.1155/2020/6705784
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