An immunohistochemistry-based classification of colorectal cancer resembling the consensus molecular subtypes using convolutional neural networks

An immunohistochemistry-based classification of colorectal cancer resembling the consensus molecular subtypes using convolutional neural networks

Abstract Colorectal cancer (CRC) represents a major global disease burden with nearly 1 million cancer-related deaths annually. TNM staging has served as the foundation for predicting patient prognosis, despite variation across staging groups. The consensus molecular subtype (CMS) is a transcriptome...

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Main Authors: Tuomas Kaprio, Jaana Hagström, Jussi Kasurinen, Ioannis Gkekas, Sofia Edin, Ines Beilmann-Lehtonen, Karin Strigård, Richard Palmqvist, Ulf Gunnarson, Camilla Böckelman, Caj Haglund
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Immunohistochemistry
Consensus molecular subtypes
Prognosis
Convoluted neural network
Online Access:https://doi.org/10.1038/s41598-025-03618-z
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https://doi.org/10.1038/s41598-025-03618-z

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