Emerging mechanomedicines informed by mechanotransduction along the integrin–cytoskeleton–nucleus axis

Mechanical forces are fundamental to the formation of normal biological tissues and the maintenance of physiological health. These forces are transmitted from the extracellular environment to the cell interior through cell–cell and cell–ECM interactions, the cytoskeleton, the LINC complex, the nucle...

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Bibliographic Details
Main Authors: Yuka Yokoyama, Nya Domkam, Hannaneh Kabir, Abdullah Mansour, Shingo Tsukamoto, Ghafar Yerima, Taiji Adachi, Mohammad R. K. Mofrad
Format: Article
Language:English
Published: AIP Publishing LLC 2025-06-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0255473
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