Maternal exposure to fullerenols impairs placental development in mice by inhibiting estriol synthesis and reducing ERα

Abstract Fullerenols, a water-soluble polyhydroxy derivative of fullerene, hold promise in medical and materials science due to their unique properties. However, concerns about their potential embryotoxicity remain. Using a pregnancy mouse model and metabolomics analysis, our findings reveal that fu...

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Bibliographic Details
Main Authors: Qing He, Jiali Yuan, Huihui Yang, Ting Du, Siqing Hu, Ling Ding, Wei Yan, Panpan Chen, Jing Li, Zhenyao Huang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-025-03121-7
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