Validity of patient-derived xenograft mouse models for lung cancer based on exome sequencing data

Patient-derived xenograft (PDX) mouse models are frequently used to test the drug efficacy in diverse types of cancer. They are known to recapitulate the patient characteristics faithfully, but a systematic survey with a large number of cases is yet missing in lung cancer. Here we report the compari...

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Bibliographic Details
Main Authors: Jaewon Kim, Hwanseok Rhee, Jhingook Kim, Sanghyuk Lee
Format: Article
Language:English
Published: BioMed Central 2020-03-01
Series:Genomics & Informatics
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Online Access:http://genominfo.org/upload/pdf/gi-2020-18-1-e3.pdf
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