A randomised controlled trial of amygdala fMRI-neurofeedback versus sham-feedback in borderline-personality disorder – systematic literature review and introduction to the BrainSTEADy trial

A randomised controlled trial of amygdala fMRI-neurofeedback versus sham-feedback in borderline-personality disorder – systematic literature review and introduction to the BrainSTEADy trial

Abstract Background Individuals with Borderline-Personality Disorder (BPD) experience intensive, unstable negative emotions. Hyperactivity of the amygdala is assumed to drive exaggerated emotional responses in BPD. Functional Magnetic Resonance Imaging (fMRI)-based neurofeedback is an endogenous neu...

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Main Authors: Christian Paret, Miroslava Jindrová, Nikolaus Kleindienst, Judith Eck, Hester Breman, Michael Lührs, Beatrix Barth, Thomas Ethofer, Andreas J. Fallgatter, Rainer Goebel, Andreas Hoell, Denise Lockhofen, Annika S. Reinhold, Simon Maier, Swantje Matthies, Christoph Mulert, Christian Schönholz, Ludger Tebartz van Elst, Christian Schmahl
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Psychiatry
Subjects:
Amygdala
Neurofeedback
Borderline-personality disorder
Randomized-controlled trial
Emotion regulation
Ecological momentary assessment
Online Access:https://doi.org/10.1186/s12888-025-07000-1
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https://doi.org/10.1186/s12888-025-07000-1

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