Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure

Sex and tissue-specificity of piRNA regulation in adult mice following perinatal lead (Pb) exposure

Lead (Pb) is a neurotoxicant with early life exposure linked to long-term health effects. Piwi-interacting RNAs (piRNAs) are small non-coding RNAs that associate with PIWIL proteins to induce DNA methylation. It remains unknown whether Pb exposure influences piRNA expression. This study evaluated ho...

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Bibliographic Details
Main Authors: Bambarendage P. U. Perera, Kai Wang, Dongyue Wang, Kathleen Chen, Alisa Dewald, Swati Sriram, Jaclyn M. Goodrich, Laurie K. Svoboda, Maureen A. Sartor, Dana C. Dolinoy
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Epigenetics
Subjects:
piRNA
lead (Pb)
ncRNA
somatic
germline
DNA methylation
Online Access:https://www.tandfonline.com/doi/10.1080/15592294.2024.2426952
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https://www.tandfonline.com/doi/10.1080/15592294.2024.2426952

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