Transcriptional features of autoimmune diabetes: differentially expressed genes in CD4+ and CD8+ subpopulations of blood T cells

Transcriptional features of autoimmune diabetes: differentially expressed genes in CD4+ and CD8+ subpopulations of blood T cells

BACKGROUND: Latent autoimmune diabetes in adults (LADA) is considered an intermediate form between type 1 (T1DM) and type 2 diabetes mellitus (T2DM). However, the molecular mechanisms underlying its unique clinical and pathogenetic features remain insufficiently studied. Identifying differentially e...

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Main Authors: I. I. Golodnikov, E. S. Podshivalova, V. I. Chechekhin, A. V. Zubritsky, A. A. Matrosova, Y. V. Dvoryanchikov, M. D. Samsonova, E. K. Markelova, Y. A. Medvedeva, T. V. Nikonova, E. V. Bondarenko, S. V. Popov, I. R. Minniakhmetov, M. V. Shestakova
Format: Article
Language:English
Published: Endocrinology Research Centre 2025-05-01
Series:Сахарный диабет
Subjects:
diabetes mellitus, type 1
latent autoimmune diabetes in adults
gene expression profiling
single cell rna sequencing
cd4-positive t-lymphocytes
cd8-positive t-lymphocytes
autoimmunity
Online Access:https://www.dia-endojournals.ru/jour/article/view/13316
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