Transcription factor networks and novel immune biomarkers reveal key prognostic and therapeutic insights in ovarian cancer

Abstract Background Understanding the tumor microenvironment (TME) is essential for the advancement of immunotherapy for ovarian cancer (OC). Nonetheless, predicting transcription factor (TF) regulation from the TME using single-cell RNA sequencing (scRNA-seq) data is challenging. Methods The OC scR...

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Bibliographic Details
Main Authors: Aiqin Zhao, Sufang Zhou, Xiaoyi Yang, Haiying Lu, Dan Zou, Xuan Zhang, Li Liu
Format: Article
Language:English
Published: Springer 2025-03-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-01788-w
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