Secondary metabolite biosynthetic gene clusters and microbial diversity as predicted by shotgun metagenomic sequencing approach in hospitals and pharmaceutical industry wastes

Secondary metabolite biosynthetic gene clusters and microbial diversity as predicted by shotgun metagenomic sequencing approach in hospitals and pharmaceutical industry wastes

Abstract Hospital and pharmaceutical industry wastes harbor a diverse microbial community influenced by their complex chemical composition, including antibiotic-rich compounds originating from soil microorganisms. This study employs a shotgun metagenomic approach to comprehensively characterize the...

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Bibliographic Details
Main Authors: Niguse Kelile Lema, Mesfin Tafesse Gemeda, Adugna Abdi Woldesemayat
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Metagenomics
Hospital wastes
Pharmaceutical wastes
Microbial diversity
Unculturable bacteria
Shotgun sequencing
Online Access:https://doi.org/10.1038/s41598-025-03467-w
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https://doi.org/10.1038/s41598-025-03467-w

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