A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds

A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds

<b>Background/Objectives:</b> Spironolactone (SP), an aldosterone inhibitor widely used to treat androgen-dependent disorders such as acne, hirsutism, and alopecia, has demonstrated therapeutic potential in both oral and topical formulations. However, SP’s low solubility and poor bioavai...

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Bibliographic Details
Main Authors: Saedah Dereiah, Muhammad Usman Ghori, Barbara R. Conway
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceutics
Subjects:
spironolactone
nano-formulations
skin
acne
wounds
transdermal drug delivery
Online Access:https://www.mdpi.com/1999-4923/17/1/27
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