Targeting nucleus pulposus cell death in the treatment of intervertebral disc degeneration
Abstract Background Intervertebral disc degeneration (IDD) is a progressive age‐related disorder characterized by the reduction in the number of nucleus pulposus cells (NPCs) and degradation of extracellular matrix (ECM), thereby leading to chronic pain and disability. The pathogenesis of IDD is mul...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-12-01
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Series: | JOR Spine |
Subjects: | |
Online Access: | https://doi.org/10.1002/jsp2.70011 |
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