Zanubrutinib and Pterostilbene Intervention in Acute Lymphoblastic Leukemia: An Action Mechanism Unveiled by Network Pharmacology and Machine Learning

Zanubrutinib, a BTK inhibitor, and pterostilbene, a natural anticancer compound, show potential in combination therapy for Acute Lymphoblastic Leukemia (ALL). Analyzing over 12,000 genes associated with ALL, key hub proteins like LYN, BTK, MYD88, and SYK were identified as crucial for leukemia progr...

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Bibliographic Details
Main Authors: Balan G Sakthi, Murugan S Arul, Prabhu Puniethaa, Kalpana B.
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:BIO Web of Conferences
Subjects:
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2025/23/bioconf_nittebio2025_02005.pdf
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