Combination of anginex gene therapy and radiation decelerates the growth and pulmonary metastasis of human osteosarcoma xenografts

Combination of anginex gene therapy and radiation decelerates the growth and pulmonary metastasis of human osteosarcoma xenografts

Abstract Investigate whether rAAV‐anginex gene therapy combined with radiotherapy could decrease growth and pulmonary metastasis of osteosarcoma in mice and examine the mechanisms involved in this therapeutic strategy. During in vitro experiment, multiple treatment regimes (rAAV‐eGFP, radiotherapy,...

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Bibliographic Details
Main Authors: Kai Zhao, Shang‐You Yang, Jun Geng, Xuan Gong, Weiming Gong, Lin Shen, Bin Ning
Format: Article
Language:English
Published: Wiley 2018-06-01
Series:Cancer Medicine
Subjects:
Anginex
anti‐angiogenesis agent
gene therapy
osteosarcoma
pulmonary metastasis
radiotherapy
Online Access:https://doi.org/10.1002/cam4.1476
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https://doi.org/10.1002/cam4.1476

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