Genomic hotspots in the DENV-2 serotype (E, NS4B, and NS5 genes) are associated with dengue disease severity in the endemic region of India.

Genomic hotspots in the DENV-2 serotype (E, NS4B, and NS5 genes) are associated with dengue disease severity in the endemic region of India.

Dengue virus (DENV) infection manifests a wide spectrum of clinical outcomes, ranging from mild fever to severe and potentially fatal disease, yet the factors driving this variability remain poorly understood. This study aims to unravel the relationship between clinical manifestations of dengue and...

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Main Authors: Varsha Ravi, Kriti Khare, Ramakant Mohite, Pallavi Mishra, Sayanti Halder, Richa Shukla, Chinky Shiu Chen Liu, Aanchal Yadav, Jyoti Soni, Kanika, Komal Chaudhary, Neha, Bansidhar Tarai, Sandeep Budhiraja, Pooja Khosla, Tavpritesh Sethi, Md Imran, Rajesh Pandey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-04-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0013034
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https://doi.org/10.1371/journal.pntd.0013034

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