Synthesis, Characterization, and Antioxidant Activity Evaluation of New N-Methyl Substituted Thiazole-Derived Polyphenolic Compounds

Synthesis, Characterization, and Antioxidant Activity Evaluation of New N-Methyl Substituted Thiazole-Derived Polyphenolic Compounds

Reactive oxygen species play a significant role in various pathological conditions, driving the need for novel, potent antioxidants. While polyphenols are known for their antioxidant properties, their limited stability and bioavailability present challenges for therapeutic applications. To address t...

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Main Authors: Alexandra Cătălina Cornea, Gabriel Marc, Ioana Ionuț, Cristina Moldovan, Anca Stana, Smaranda Dafina Oniga, Adrian Pîrnău, Laurian Vlase, Ilioara Oniga, Ovidiu Oniga
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
Subjects:
Hantzsch heterocyclization
polyphenols
thiazole derivatives
ROS
oxidative stress
in vitro
Online Access:https://www.mdpi.com/1420-3049/30/6/1345
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