Proximal Tubular Injury in Medullary Rays Is an Early Sign of Acute Tacrolimus Nephrotoxicity

Tacrolimus (FK506) is one of the principal immunosuppressive agents used after solid organ transplantations to prevent allograft rejection. Chronic renal injury induced by tacrolimus is characterized by linear fibrosis in the medullary rays; however, the early morphologic findings of acute tacrolimu...

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Bibliographic Details
Main Authors: Diane Cosner, Xu Zeng, Ping L. Zhang
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2015/142521
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