How HIV-1 Uses the Metabolite Inositol Hexakisphosphate to Build Its Capsid

The HIV-1 capsid is one of virology’s most iconic structures, yet how it assembles has long remained elusive. Remarkably, the capsid is made from just a single protein, CA, which forms a lattice of ~250 hexamers and exactly 12 pentamers. Conical capsids form inside budded virions during maturation,...

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Bibliographic Details
Main Author: Leo C. James
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/17/5/689
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