Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury

Microvesicles carrying EV71 virions cross BBB through endocytic pathway to induce brain injury

Abstract Enterovirus 71 (EV71) is a major etiologic pathogen for hand-foot-and-mouth disease (HFMD) in young children. Severe cases of EV71 infection could lead to neurological complications and even death, while the mechanism inducing neurological complications remains poorly understood. In this st...

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Bibliographic Details
Main Authors: Xiaoyan Tian, Bingxin Liu, Linrun Li, Meng Yuan, Qiao You, Rui Zhang, Deyan Chen, Min Cheng, Nan Zheng, Miao He, Zhiwei Wu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cell Communication and Signaling
Subjects:
Microvesicles
EV71 virus
Blood-brain barrier
Endocytosis
Damaged mitochondria
Online Access:https://doi.org/10.1186/s12964-025-02195-y
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https://doi.org/10.1186/s12964-025-02195-y

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