TREM2 promotes the formation of a tumor-supportive microenvironment in hepatocellular carcinoma

TREM2 promotes the formation of a tumor-supportive microenvironment in hepatocellular carcinoma

Abstract Background Triggering receptor expressed on myeloid cells 2 (TREM2), a surface receptor predominantly expressed on myeloid cells, is a major hub gene in pathology-induced immune signaling. However, its function in hepatocellular carcinoma (HCC) remains controversial. This study aimed to eva...

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Bibliographic Details
Main Authors: Hanrui Guo, Meiling Wang, Caiya Ni, Chun Yang, Chunxue Fu, Xiaoman Zhang, Xueling Chen, Xiangwei Wu, Jun Hou, Lianghai Wang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
TREM2
HCC
CD8
Glycolysis
PKM2
Online Access:https://doi.org/10.1186/s13046-025-03287-w
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https://doi.org/10.1186/s13046-025-03287-w

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