The local pulsatile parathyroid hormone delivery system induces the osteogenic differentiation of dental pulp mesenchymal stem cells to reconstruct mandibular defects

Abstract Background Tumors and injuries often lead to large mandibular defects. Accelerating the osteogenesis of large bone defect areas is a major concern in current research. In this study, dental pulp mesenchymal stem cells (DPSCs) were used as seed cells, and the local pulsatile parathyroid horm...

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Bibliographic Details
Main Authors: Yuanyuan Jia, Mianmian Duan, Yan Yang, Duchenhui Li, Dongxiang Wang, Zhenglong Tang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Stem Cell Research & Therapy
Online Access:https://doi.org/10.1186/s13287-025-04258-w
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