CAR-T cell therapy clinical trials: global progress, challenges, and future directions from ClinicalTrials.gov insights

Chimeric antigen receptor T (CAR-T) cell therapy has undergone vigorous development in recent years, yet it still faces significant challenges and difficulties in its clinical application and further development. A systematic synthesis of global trends in CAR-T clinical trials is essential to identi...

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Bibliographic Details
Main Authors:	Li-Ya Cao, Yue Zhao, Yang Chen, Pan Ma, Jiang-Chuan Xie, Xin-Mei Pan, Xin Zhang, Yong-Chuan Chen, Qian Wang, Lin-Li Xie
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Immunology
Subjects:	chimeric antigen receptor T-cell clinical trials clinicaltrials.gov hematological malignancies solid tumors publication following search queries: condition/disease or intervention/treatment: “CAR T”
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1583116/full
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CAR-T cell therapy clinical trials: global progress, challenges, and future directions from ClinicalTrials.gov insights

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