CAR-T cell therapy clinical trials: global progress, challenges, and future directions from ClinicalTrials.gov insights

Chimeric antigen receptor T (CAR-T) cell therapy has undergone vigorous development in recent years, yet it still faces significant challenges and difficulties in its clinical application and further development. A systematic synthesis of global trends in CAR-T clinical trials is essential to identi...

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Bibliographic Details
Main Authors: Li-Ya Cao, Yue Zhao, Yang Chen, Pan Ma, Jiang-Chuan Xie, Xin-Mei Pan, Xin Zhang, Yong-Chuan Chen, Qian Wang, Lin-Li Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1583116/full
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