ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria

ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria

BackgroundMalaria in pregnancy is a major public health issue, particularly among vulnerable populations in malaria-endemic sub-Saharan African countries. To mitigate its risks, WHO recommends sulphadoxine-pyrimethamine (SP) for chemoprevention and artemisinin-based combination therapy (ACT) to trea...

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Bibliographic Details
Main Authors: Adebanjo Jonathan Adegbola, Leonard Ndwiga, Kevin Wamae, Victor Osoti, Oluseye Oladotun Bolaji, Philip Bejon, Lynette Isabella Ochola-Oyier
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Genetics
Subjects:
malaria
chemoprevension
surveillance
genotyping
sequencing
resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1470156/full
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https://www.frontiersin.org/articles/10.3389/fgene.2024.1470156/full

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