A novel IgG-Fc-Fused multiepitope vaccine against Brucella: robust immunogenicity

A novel IgG-Fc-Fused multiepitope vaccine against Brucella: robust immunogenicity

Abstract Brucellosis is one of the most common zoonotic diseases caused by Brucella spp. However, there is currently no Brucella vaccine available for humans. Although some attenuated live vaccines have been approved for animals, their protective efficacy is suboptimal. In previous studies, we utili...

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Main Authors: Aodi Wu, Yuting Zhang, Caidong Liu, Kaiat Zhumanov, Tao He, Kexin Yan, Honghuan Li, Shuangshaung Fu, Xin Li, Wenxiang Zhang, Chuang Meng, Changsuo Zhang, Jinliang Sheng, Zhongchen Ma, Mingguo Xu, Junbo Zhang, Jihai Yi, Yueli Wang
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Microbial Cell Factories
Subjects:
Brucella
Multiple epitopes
Vaccines immune response
Online Access:https://doi.org/10.1186/s12934-025-02713-0
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https://doi.org/10.1186/s12934-025-02713-0

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