Structural convergence and membrane interactions of Aβ1-42 along the primary nucleation process studied by solid state NMR
Abstract Non-specific disruption of cellular membranes induced by amyloidogenic aggregation of β-amyloid (Aβ) peptides remains a viable cytotoxicity mechanism in Alzheimer’s disease (AD). Obtaining structural information about the intermediate states of Aβ-membrane systems and their molecular intera...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-025-01537-8 |
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