Prognostic value of positive lymph node ratio, tumor deposit, and perineural invasion in advanced colorectal signet-ring cell carcinoma

Prognostic value of positive lymph node ratio, tumor deposit, and perineural invasion in advanced colorectal signet-ring cell carcinoma

BackgroundThe aim of this study was to assess the prognostic significance of positive lymph node ratio (LNR), tumor deposits (TD), and perineural invasion (PNI) in advanced colorectal signet-ring cell carcinoma (SRCC).MethodsA multicenter retrospective cohort analysis was conducted involving 677 pat...

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Bibliographic Details
Main Authors: Liang Chu, Han Wang, Tao Ling, Shuhan Feng, Yucheng Ding, Yan Zhang, Ying Pan, Cenzhu Wang, Xiaohong Wang, Lei Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
colorectal signet ring cell carcinoma
lymph node ratio
tumor deposit
perineural invasion
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1617787/full
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https://www.frontiersin.org/articles/10.3389/fmolb.2025.1617787/full

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