Horizontal acquisition of prokaryotic hopanoid biosynthesis reorganizes membrane physiology driving lifestyle innovation in a eukaryote

Abstract Horizontal gene transfer is a source of metabolic innovation and adaptation to new environments. How new metabolic functionalities are integrated into host cell biology is largely unknown. Here, we probe this fundamental question using the fission yeast Schizosaccharomyces japonicus, which...

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Bibliographic Details
Main Authors: Bhagyashree Dasari Rao, Elisa Gomez-Gil, Maria Peter, Gabor Balogh, Vanessa Nunes, James I. MacRae, Qu Chen, Peter B. Rosenthal, Snezhana Oliferenko
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58515-w
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