Computational drug repurposing in Parkinson’s disease: Omaveloxolone and cyproheptadine as promising therapeutic candidates

Computational drug repurposing in Parkinson’s disease: Omaveloxolone and cyproheptadine as promising therapeutic candidates

Background: Parkinson's disease (PD), a prevalent and progressive neurodegenerative disorder, currently lacks effective and satisfactory pharmacological treatments. Computational drug repurposing represents a promising and efficient strategy for drug discovery, aiming to identify new therapeuti...

Full description

Saved in:
Bibliographic Details
Main Authors: Xin Guo, Jie Wang, Hongyang Fan, Wanying Tao, Zijing Ren, Xingyue Li, Suyu Liu, Peiyang Zhou, Yingzhu Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
Subjects:
computational repurposing
Parkinson’s disease
Omaveloxolone
cyproheptadine
MAPK/NF κ B signaling pathway
Keap1-Nrf2/ARE signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1539032/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2025.1539032/full

Similar Items