Breast cancer homologous recombination deficiency prediction from pathological images with a sufficient and representative Transformer

Breast cancer homologous recombination deficiency prediction from pathological images with a sufficient and representative Transformer

Abstract Homologous recombination deficiency (HRD) has been recognized as a key biomarker for poly-ADP ribose polymerase inhibitors (PARPi) and platinum-based chemotherapy in breast cancer (BC). HRD prediction typically relies on molecular biology assays, which have a high turnaround time, and cost....

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Main Authors: Haijing Luan, Taiyuan Hu, Jifang Hu, Weier Liu, Kaixing Yang, Yue Pei, Ruilin Li, Jiayin He, Yajun Gao, Dawei Sun, Xiaohong Duan, Rui Yan, S. Kevin Zhou, Beifang Niu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00950-5
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https://doi.org/10.1038/s41698-025-00950-5

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