Multi-omics analysis revealed significant metabolic changes in brain cancer cells treated with paclitaxel and/or topotecan

Multi-omics analysis revealed significant metabolic changes in brain cancer cells treated with paclitaxel and/or topotecan

Glioblastoma (GBM) stands as the most common primary malignant brain tumor. Despite the best standard therapies, GBM survivors have a brief survival time, about 24 months on average. The treatment is troublesome because the cancer cells may not respond well to specific therapies as they grow within...

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Bibliographic Details
Main Authors: Ahlam M. Semreen, Leen Oyoun Alsoud, Mohammad H. Semreen, Munazza Ahmed, Hamza M. Al-Hroub, Raafat El-Awady, Wafaa S. Ramadan, Ahmad Abuhelwa, Yasser Bustanji, Nelson C. Soares, Karem H. Alzoubi
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
Proteomics
Metabolomics
Brain Cancer
Therapy
Drug treatment
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024154515
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