Kharon Is Crucial for <i>Trypanosoma cruzi</i> Morphology but Does Not Impair In Vitro Infection

Kharon Is Crucial for <i>Trypanosoma cruzi</i> Morphology but Does Not Impair In Vitro Infection

Chagas disease, caused by <i>Trypanosoma cruzi</i>, is a neglected tropical disease with few options for treatment and no available vaccine. Deletion mutants for live attenuated vaccines, particularly deletions of proteins related to the cytoskeleton, have been widely tested in related p...

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Bibliographic Details
Main Authors: Jose Luis Saenz-Garcia, Normanda Souza-Melo, Juliana Severo Miranda, Beatriz Borges, Lisandro A. Pacheco-Lugo, Jose M. Quintero-Solano, Nilmar Moretti, Richard Wheeler, Lia C. Soares-Medeiros, Wanderson D. DaRocha
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pathogens
Subjects:
<i>Trypanosoma cruzi</i>
morphology
CRISPR/Cas9
Online Access:https://www.mdpi.com/2076-0817/14/4/312
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