Split RNA switch orchestrates pre- and post-translational control to enable cell type-specific gene expression
Abstract RNA switch is a synthetic RNA-based technology that controls gene expression in response to cellular RNAs and proteins, thus enabling cell type-specific gene regulation and holding promise for gene therapy, regenerative medicine, and cell therapy. However, individual RNA switches often lack...
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| Main Authors: | Itsuki Abe, Hirohisa Ohno, Megumi Mochizuki, Karin Hayashi, Hirohide Saito |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-60392-2 |
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