Group B Streptococci lyse endothelial cells to infect the brain in a zebrafish meningitis model.

To cause meningitis, bacteria move from the bloodstream to the brain, crossing the endothelial cells of the blood-brain barrier. Most studies on how bacteria cross the blood-brain barrier have been performed in vitro using cultured endothelial cells, due to a paucity of animal models. Group B Strept...

Full description

Saved in:
Bibliographic Details
Main Authors: Sumedha Ravishankar, Samantha M Tuohey, Nicole O Ramos, Satoshi Uchiyama, Megan I Hayes, Kalisa Kang, Victor Nizet, Cressida A Madigan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003236
Tags: Add Tag
No Tags, Be the first to tag this record!